{"product_id":"cible-skin-skinbooster-1-lgvty®-7-5","title":"Cible Skin - Skinbooster 1-LGVTY® 7.5%","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cstrong\u003eSkinbooster 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003e7.5%\u003c\/strong\u003e\u003cspan\u003e, rich in \u003c\/span\u003e\u003cstrong\u003ecollagen precursor peptides\u003c\/strong\u003e\u003cspan\u003e, sustainably enhances the biological performance of the skin. It provides \u003c\/span\u003e\u003cstrong\u003ecomprehensive anti-inflammatory protection\u003c\/strong\u003e\u003cspan\u003e by addressing both \u003c\/span\u003e\u003cstrong\u003eacute and chronic inflammation\u003c\/strong\u003e\u003cspan\u003e, while also offering targeted defense against the main accelerators of skin aging, including \u003c\/span\u003e\u003cstrong\u003eoxidative stress and microbiome imbalance\u003c\/strong\u003e\u003cspan\u003e.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eAt the same time, it activates the fundamental mechanisms of \u003c\/span\u003e\u003cstrong\u003eskin longevity\u003c\/strong\u003e\u003cspan\u003e by stimulating the biological pathways involved in cellular renewal, firmness, and maintaining healthy, functional skin over time.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eBenefits\u003c\/strong\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cmeta charset=\"utf-8\"\u003e \u003cspan class=\"title\"\u003eSpots: Melanin reduction. It supports the regulation of melanin synthesis to accompany task-oriented protocols and improve skin tone uniformity over time.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"title\"\u003e\u003cmeta charset=\"utf-8\"\u003eWrinkles: Collagen synthesis. \u003cmeta charset=\"utf-8\"\u003eIt supports collagen and elastin markers to accompany the remodeling dynamics induced by the procedure and strengthen skin firmness over time.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan class=\"title\"\u003e\u003cmeta charset=\"utf-8\"\u003eTightness: Hyaluronic acid synthesis. \u003cmeta charset=\"utf-8\"\u003eIt supports hyaluronic acid markers and overall skin performance to promote a smoother surface and refined skin quality.\u003c\/span\u003e\u003cspan class=\"title\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cp class=\"text-align-center\"\u003e\u003cstrong\u003eComparison of skin explants from the clinical study\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"text-align-center\"\u003e\u003cstrong\u003eStress situation vs. 1-LGVTY + stress situation\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"subsection expandable expanded\" data-ordinal=\"1\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"ordinal\"\u003e1. \u003c\/span\u003eSignificant reduction in inflammation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"layout-wrapper collapsing-content\"\u003e\n\u003cdiv class=\"inner\"\u003e\n\u003cdiv class=\"layout-group\"\u003e\n\u003cp\u003eInflammatory stresses, whether acute or chronic, impact skin longevity. This inflammation, often referred to as inflammaging, alters cellular functions, disrupts the skin barrier, and accelerates the decline of the skin’s biological performance. In our models using UV-exposed explants, the patented 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003etechnology significantly reduces the cytokines IL-1α and IL-6, two key biomarkers of inflammatory responses involved in the progressive degradation of skin functions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"ordinal\"\u003e2. \u003c\/span\u003eNet reduction in oxidation\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"layout-wrapper collapsing-content\"\u003e\n\u003cdiv class=\"inner\"\u003e\n\u003cdiv class=\"layout-group\"\u003e\n\u003cp\u003eCutaneous oxidative stresses correspond to an imbalance between the production of reactive oxygen species (ROS). Regulating oxidative stress plays a key role in the potential for skin longevity. When ROS exceed natural antioxidant capacities, they alter lipids, structural proteins, and fibers, compromising the biological performance of the skin. In a model of explants subjected to acute oxidative stress, 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003esignificantly reduces ROS production in keratinocytes, fibroblasts, and the extracellular matrix. By decreasing protein oxidation by 237%, the technology restores the skin’s ability to resist, recover, and preserve its longevity potential.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"see-details\" data-subsection-handle=\"stressInflammatoires\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"ordinal\"\u003e3. \u003c\/span\u003eMicrobiome rebalancing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"layout-wrapper collapsing-content\"\u003e\n\u003cdiv class=\"inner\"\u003e\n\u003cdiv class=\"layout-group\"\u003e\n\u003cp\u003eImbalances in the skin microbiome constitute real microbial stresses, influencing skin longevity. They disrupt skin homeostasis and weaken its natural defense mechanisms. In explants subjected to environmental stress (UV and pollution), 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003estimulates the expression of antimicrobial peptides, particularly β-defensins-2, as well as that of immunomodulatory mediators, which contribute to maintaining a functionally stable microbiome essential for promoting skin longevity.\u003c\/p\u003e\n\u003ch4 class=\"\"\u003eThe actions of 1-LGVTY on biomarkers of skin longevity:\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"ordinal\"\u003e1. \u003c\/span\u003eDecrease in melanin\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"layout-wrapper collapsing-content\"\u003e\n\u003cdiv class=\"inner\"\u003e\n\u003cdiv class=\"layout-group\"\u003e\n\u003cp\u003eThe regulation of melanogenesis is essential for skin longevity, as excessive or imbalanced melanin production indicates a disruption of the skin’s protective mechanisms. In an explant model subjected to pigmentary stress (UV\/inflammation), 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003ereduces melanin levels by 80% and decreases tyrosinase activity by 125%, improving pigmentation and skin longevity while evening out the complexion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"ordinal\"\u003e2. \u003c\/span\u003eIncrease in collagen synthesis\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"layout-wrapper collapsing-content\"\u003e\n\u003cdiv class=\"inner\"\u003e\n\u003cdiv class=\"layout-group\"\u003e\n\u003cp\u003eThe quality of the collagen network is one of the most determining indicators of skin longevity. Over time, its synthesis decreases while its degradation accelerates, leading to loss of density, firmness, and the appearance of wrinkles. In a model of explants subjected to combined UV + pollution stress, 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003epreserves type I collagen fibers and stimulates their production by 114%, enhancing the structural longevity of the dermis and the stability of its extracellular matrix.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan class=\"ordinal\"\u003e3. \u003c\/span\u003eIncrease in hyaluronic acid synthesis\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv class=\"layout-wrapper collapsing-content\"\u003e\n\u003cdiv class=\"inner\"\u003e\n\u003cdiv class=\"layout-group\"\u003e\n\u003cp\u003eHyaluronic acid, through its interaction with the CD44 receptor, modulates key longevity processes such as hydration, skin repair, and cell signaling. It ensures cellular cohesion, deep hydration, and the skin’s ability to regenerate. In a model of explants subjected to UV and pollution, tissues treated with 1-LGVTY\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eshow a 98% stimulation of CD44 receptor expression, revealing better preservation of endogenous hyaluronic acid, enhanced cellular cohesion, and strengthening of the skin barrier essential for skin longevity.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cstrong\u003eIngredient List\u003c\/strong\u003e\u003cbr\u003eAqua \/ Water \/ Eau, Pentylene Glycol, Inulin, Chlorogenic Acids, Sodium Polyacrylate Starch, Arginine, Glycerin, Hydrolyzed Sodium Hyaluronate, Alpha-glucan Oligosaccharide, Sodium Hyaluronate, Scutellaria Baicalensis Root Extract, Cellulose Gum, Ceratonia Siliqua (Carob) Gum, Sodium Carboxymethyl Beta-glucan, Xanthan Gum, Citric Acid, Collagen, Cellulose, Fructose, Glucose, Sodium Benzoate, Succinic Acid, Potassium Sorbate\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eApplication tips:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eApply 1-2 times a week on the face, neck, and décolleté.\u003c\/span\u003e\u003cmeta charset=\"utf-8\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cmeta charset=\"utf-8\"\u003e\n\u003cstrong\u003eInformation regarding environmental characteristics\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eMainly recyclable container\u003c\/li\u003e\n\u003cli\u003eMainly recyclable packaging\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Freia247","offers":[{"title":"30ml","offer_id":48321647476963,"sku":null,"price":315.0,"currency_code":"SGD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0155\/6634\/0144\/files\/foredm.png?v=1772261294","url":"https:\/\/freia247.sg\/products\/cible-skin-skinbooster-1-lgvty%c2%ae-7-5","provider":"Freia247","version":"1.0","type":"link"}